Sunday, April 13, 2008

Fetal Cells Transplanted into the Brain to Treat Parkinson’s Disease May Not Function Long Term

 Fetal Cells Transplanted into the Brain to Treat Parkinson’s Disease May Not Function Long TermRush University Medical Center -Newswise Science News, (06 Apr 2008)"Neurons grafted into the brain of a patient with Parkinson’s disease fourteen years ago have developed Lewy body pathology, the defining pathology for the disease, according to research by Jeffrey H. Kordower, PhD, and associates and published in the April 6 issue of Nature Medicine. "..."“These findings give us a bit of pause for the value of cell replacement strategy for Parkinson’s disease,” said Kordower. “We still need to vigorously investigate this approach among the full armament of surgically-delivered Parkinson’s disease therapies. While it is not clear to us whether the same fate would befall stem cell grafts, the next generation of cell replacement procedures, this study does suggest that grafted cells can be affected by the disease process.”"..."The collaborative research study described in the article involves Rush, Mt. Sinai School of Medicine, New York, and the University of South Florida, Tampa, In it, individuals with Parkinson’s disease received fetal cell transplants to reverse the loss in the brain of striatal dopamine"...Posted by msredsonyas to Cognitive Sciences-Neuro-Philosophy-Psychiatry-Psychology NeuroChemical or Synaptic Signaling Stem Cell Lines-ES-HES Efficacy and or safety studies Medical Sciences on Mon Apr 07 2008 at 04:22 UTC | info | related